Jarrow Formulas^® SAMe 200  provides a full 200 mg SAMe (net yield) from 400 mg of SAMe tosylate disulfate. SAMe 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

With More of the Biologically Active S,S than R,S Form
Found in all living cells, SAMe is a metabolite of methionine (an essential amino acid). SAMe is a chiral molecule consisting of two forms: (S,S) SAMe and (R,S) SAMe. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.  Jarrow Formulas^® SAMe  is made by microbiological fermentation and then processed without chemical solvents to preserve 68-80% (S,S) SAMe.

SAMe  supports:

Brain Metabolism and Mood
SAMe methylation reactions are involved in the synthesis of phosphatidylcholine, a substantial constituent of grey matter within the brain and cellular membranes. It has also been proposed to be involved in the formation or metabolism of neurotransmitters, which helps to support a balanced mood.

Joint Health
SAMe supports the production of healthy connective tissue through transulfuration. In this transsulfuration process, critical components of connective tissue known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAMe metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate, the building blocks of cartilage.

Liver Function
SAMe supports the synthesis of glutathione (GSH), which is critical for antioxidant defenses and liver functions including phase II detoxification.

Jarrow Formulas^® SAMe 200  is foil blister-packed to maximize stability and provides 200 mg S-Adenosyl Methionine derived from 400 mg of SAMe Tosylate Disulfate.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.