The liver is the body’s major metabolic organ. It processes, packages, stores, and ships out carbohydrates, fats, proteins, and micronutrients. It is responsible for the breakdown and elimination of alcohol, toxins, hormones, and medications, as well as for the synthesis of vital
proteins, such as albumin, prealbumin, and clotting factors. It may be stated that the health of the body depends on the health of the liver. Research suggests that providing targeted nutrition supplementation may help support liver function and health.

N-Acetyl-Cysteine (NAC) An acetylated derivative of the sulfurcontaining amino acid L cysteine, NAC may promote the synthesis of glutathione—a tripeptide that is active in detoxification and antioxidant systems. Glutathione also may support a healthy defense against hepatotoxic environmental pollutants, gamma-radiation, and other potential toxins.

Alpha-Lipoic Acid Sometimes referred to as thioctic acid, alpha-lipoic acid is both water- and fat-soluble. It may support glutathione, may help regenerate antioxidant vitamins C and E, may help maintain the ratio of reduced to oxidized CoQ10 in the mitochondria, and may help support healthy levels of nitric oxide in the liver and kidney. The redox couple of lipoic acid and dihydrolipoic may stabilize NF-kappaB transcription and may help support healthy immune functions in the body.

Milk Thistle Seed Extract Silymarin, the active component in milk thistle, has a history of use in potentially promoting liver health. It may support antioxidant activity, may neutralize toxins, and also may protect hepatocytes’ genetic material. Like alpha-lipoic acid, silymarin supports production of cellular glutathione. Its actions in the liver include maintaining normal levels of fat peroxidation and fibrous tissue formation; potentially supporting a healthy immune response and the natural response to inflammation; and potentially promoting protein synthesis and normal regeneration of liver tissue. A randomized placebo-controlled study of 103 individuals suggested that silymarin yielded statistically positive results and was well tolerated.

Selenium (as selenomethionine) An important coenzyme for the glutathione peroxidase detoxification system, selenium also may support the endogenous antioxidant defenses of hepatocytes by upregulating their manganese superoxide dismutase (MnSOD) expression. At the same time, selenium appears to potentially support healthy cytokine balance by affecting interleukin-6 (IL-6) transcription in Kupffer cells (liver-based macrophages). Kupffer cells play a crucial role in maintaining normal structure and function in the liver. Supporting their function and the body’s normal inflammatory response in turn supports liver health overall.

Upon studying targeted nutrition support for liver health, researchers combined alpha-lipoic acid, silymarin, and selenium to obtain a balanced and low-cost approach to liver support. These three ingredients plus NAC are all present in Liver Protect™ to support liver health, antioxidant activity, and the body’s natural immune defenses.

» May Support Healthy Liver Function
» May Support Cytokine Balance
» May Support Glutathione Production
» May Protect Liver Tissue

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.