K2-D3 Max is formulated for those who need a more substantial presence of vitamin K2, delivering 180 mcg per serving. The combination of highly bioavailable and bioactive menaquinone-7 (MK-7) with vitamin D3 provides complementary benefits for bone and cardiovascular health.

Vitamin K (as MK-7)
The body has limited vitamin K storage capacity compared with other lipophilic vitamins. Vitamin K rapidly depletes without regular dietary intake, yet a small reserve is recycled through a complex oxidation–reduction cycle. The primary function of vitamin K is as a cofactor in producing blood coagulation factors in the liver. Vitamin K also has rather complicated physiological roles in the
carboxylation of the proteins involved in promoting bone mineralization and inhibiting arterial calcification.1,2 These physiological roles directly affect bone health and arterial elasticity, respectively. Supplemental vitamin K can be found in the 3 following forms: synthetic
K1; menaquinone-4 (MK-4), which is structurally similar to K1; and natural, long-chain menaquinone-7 (MK-7), which provides the highest vitamin K activity. Structural variations between K1 and K2 impact their bioavailability and bioactivity. Menaquinone-7, with its longer side chain, is very hydrophobic.

Compared with K1, the physiochemical properties of MK-7 make it highly transportable by plasma lipoproteins, increase its extrahepatic (bones, arteries, etc) availability, and result in its long half-life. Findings from a series of studies comparing the in vivo properties of orally administered K1 and MK-7 demonstrated better bioavailability and utilization of MK-7.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.