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The bio-active form of CoQ10 that may support antioxidant activity, cytoprotection and energy production in the body.
Ubiquinol, the bioactive form of CoQ10, may support antioxidant activity by neutralizing free radicals and toxic superoxides. It may support cytoprotection by minimizing membrane lipid peroxidation as well. The patented, lipid-stabilized form of ubiquinol in CoQmax™ Ubiquinol is present for enhanced bioavailability. Ubiquinol, representing over 90% of total body CoQ10, is efficiently converted to the energy-generating form as the body needs it.
CoQ10 and the CoQ10 cycle play fundamental roles in the antioxidant and energy systems of the body. CoQ10 is produced in the mitochondria, where it directly participates in energy production by accepting electrons in the electron transport chain. Through the action of an oxidoreductase enzyme, the inactive form is rapidly converted to ubiquinol, the lipid-soluble form that supports antioxidant activity throughout the body. Conversion of inactive form to ubiquinol declines with age, particularly after age 40. Supplementation may help maintain normal levels of ubiquinol in the body as well as address drug-induced nutrient depletion of CoQ10. Until recently, the ubiquinol form had not been effective as a supplement because it was chemically unstable and easily oxidized. CoQmax Ubiquinol™ contains a patented, absorbable form of ubiquinol that maintains its structure and stability in the gastrointestinal environment.
Antioxidant Status Oxidative stress is detrimental to the integrity and function of cell membranes and tissues, and ultimately to DNA itself. Antioxidant status must be maintained throughout the body in order to protect vulnerable cells. Research indicates that ubiquinol supports antioxidant activity, including the regeneration of vitamins C and E, helping to maintain normal levels of free radical activity in the body. Researchers also suggest a possible role for CoQ10 in redox control of cell signaling and gene expression.
Heart Health Research suggests that patients experienced significant support of cardiac function after receiving supplemental ubiquinol (an average 450-580 mg per day). These patients achieved more desirable levels of serum CoQ10. Researchers suggest that ubiquinol had dramatically improved absorption. Research on the elderly also appears to indicate that supplemental CoQ10 can increase tolerance to aerobic stress in cardiac tissue.
Toxicity: CoQ10 is safe as a dietary supplement. Toxicity is unlikely up to a daily intake of 1200 mg/d, although typical dosages have been 100 to 200 mg/d. In preclinical studies, ubiquinol's No-Observed-Adverse-Effect Level is 300-600 mg/kg.
Enhancing Healthcare Team Outcomes: CoQ10 is a safe, popular dietary supplement that is continuously being studied as an adjunctive treatment for several medical conditions, including congestive heart failure, type-2 diabetes mellitus with hyperlipidemia, fibromyalgia, mitochondrial disorders, Peyronie disease, myalgia, depression, migraines, and polycystic ovary syndrome.
For more comprehensive information on Ubiquinol, please follow the link to this article published in the National Library of Medicine: https://www.ncbi.nlm.nih.gov/
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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