GABA is the primary inhibitory neurotransmitter in the brain; it is important for calm and sleep.

L-theanine is an amino acid that acts as a glutamate receptor antagonist. It has been linked to the generation of alpha brain waves, indicating a state of relaxation.

Melatonin is a hormone important for the regulation of the sleep-wake cycle; it has been shown to improve the onset of sleep and to increase alpha brain waves.

Valerian root extract modulates GABA-A receptors to increase the amount of GABA in the brain.

Lemon Balm leaf extract has been shown to inhibit the enzyme GABA transaminase, which may increase levels of GABA in the brain. It also contains rosmarinic acid, which has been shown to normalize GABA and glutamate activity altered by stress when combined with valerian root.

5-HTP crosses the blood-brain barrier and is a precursor to serotonin and melatonin. Serotonin is important for regulating mood and sleep-wake function. 

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.